Odds are your dog will tolerate Phenobarbital just fine and won’t have muscle weakness issues like mine did. Longer term side effects may be increased appetite, and, occasionally, increased thirst and urination. Phenobarbital works by reducing the neuron activity in the dog’s brain – think of it as a central nervous system depressant. Here are some of the common side effects: Lethargy Sedation Anxiety Restlessness Loss of coordination Increased thirst or appetite Weight gain Increased urination Anemia Liver damage (long-term use) My 4 year old German shepherd suffers from seizures and being treated with 97.2 mg 2x a day. Anticonvulsant drugs like phenobarbital are used to treat seizures in dogs, including those caused by epilepsy. Here are some side effects of Phenobarbital to watch out for: A less frequent but more serious potential side effect of phenobarbital is liver disease. Traveling with Pets. The drug boosts up and strengthens the activity of gamma-aminobutyric acid in the brain, a chemical known to stop signals from crossing one neuron to another. ... long-term side effect of phenobarbital therapy is liver toxicity. decreased dosage. Side Effects What are the side effects of Phenobarbital?. Antihistamines 3. Several other side effects are possible with long-term monitor your dog's behavior and blood levels so that you'll notice Each These may offer a Anemia 8. Long-term side effects of Phenobarbital include frequent urination, excessive drinking and eating. Do not use this medication in pets with liver, lung, or kidney disease or those that are allergic to barbiturates. This particular side effect only impacts a small percentage of These side effects will normally diminish in time. Upset stomach or throwing up. Diazepam (and other central nervous system depressants) 5. Drugs to be avoided, if possible, in a dog on phenobarbital are … In most cases, long term damage occurs after the three months mark. Phenobarbital works by reducing neuronal activity and this is known to cause side effects in dogs by affecting toher neurons in your dogs body. About 60 to 80% of dogs suffering from epilepsy can be effectively controlled by PB as clinical testimonies and records have indicated. Other potential long-term adverse effects: Lethargy / Sedation Anxiety / Restlessness Loss of coordination Weight gain Anemia Liver damage Slideshow Surprising Things You Didn't Know About Dogs and Cats; News & Experts News & Experts. TPLO (Tibial Plateau Leveling Osteotomy) in Dogs. Beta adrenergic blocker 4. in dogs. ... Total Ear Canal Ablation and Ventral Bulla Osteotomy (TECA) for End-Stage Ears in Dogs and Cats. Phenobarbital and side effects on large dog . time can lead to fatal phenobarbital side effects. Increase in water intake 5. Some phenobarbital side effects for limiting seizures in people is not generally effective for dogs. subtle changes and have the opportunity to take action before it's too The administration of phenobarbital orally every eight hours in IEDs with decreased phenobarbital … Albeit being generally safe for dogs, Phenobarbital is considered as an extra-label drug by the Food and Drug Administration. remedies. Despite side effects, phenobarbital is Liver Damage Most Dangerous Side Effect of Phenobarbital Just be sure you understand any possible implications Treatment with phenobarbital aims to reduce the number and severity of seizures, but may not eliminate fits altogether. Anxiety 2. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Feeling sleepy. Weight gain Phenobarbital may react with these drugs: 1. They often start without any warning, sometimes with a cause. All drugs may cause side effects. In all dogs the side effects of the antiepileptic medication treatment improved. It is effective, safe if used responsibly, reasonably priced, and conveniently dosed all of which makes it a popular choice. Liver damage can be prevented if detected in time, hence most veterinarians highly advised to let your dog undergo routine blood work to observe well the liver condition while your dog is still on medication. clear up within a few weeks of continual use. Despite this rather long list of documented long-term effects associated with chronic use of phenobarbital either as a medicinal drug or a drug of abuse, the sources also suggest that there may be long-term side effects associated with phenobarbital use that have not been reported. Side effects are observed to be neurological, and dog owners should not worry about these because these will only last within the first few weeks of therapy and will gradually subside in time. Other drugs with fewer side effects are now available, but come with a hefty price tag. If you notice these signs in your pet, contact your veterinarian immediately. I believe the most common side effects are increased drinking and hunger. Phenobarbital Side Effects. In layman’s term, PB helps to ease out these neurons so they relax instead of becoming stressed out. Eye Injuries: First Aid. is when phenobarbital is combined with other medications or natural Often referred to as “phenol” and abbreviated as PB, Phenobarbital is a barbiturate that was first used to treat and control human epilepsy way back 1912 and is now being used in dogs for the same purpose. Excessive Hunger and Thirst. long-term. Esophagostomy Tube (E-tube) Care. wish to avoid it altogether. What are some other side effects of Phenobarbital Tablets? Phenobarbital side effects can occur both over the short-term and These are sedation, ataxia (loss of coordination), and the 3 P's: polydipsia (excessive thirst), polyuria (excessive urination) and polyphagia (excessive eating). Chloramphenicol 10. If your dog or cat is receiving phenobarbital, it is important not to withdraw the medicatio… The Side Effets of Phenobarbital for Dogs. If a negative reaction occurs, please call your veterinary office. These are not all of the side effects that … Should I be worried about the side effects of phenobarbital?Dr. Scarring of the Phenobarbital for dogs is a popular, and often- prescribed medication used to treat seizures in dogs. Corticosteroids 6. Lethargy 3. dogs on the drug, but the severity of the outcome makes it important to Applies to phenobarbital: oral elixir, oral tablets, parenteral injection Side effects include: Residual sedation, drowsiness, lethargy, vertigo, nausea, vomiting, headache. Opiate agonists 7. mentioned earlier, and potassium bromide. Phenothiazine 8. I know if my dog had a seizure, I would totally panic. Furosemide 12. significantly lower risk of side effects when used independently and Blood issues are pretty rare, so just go along with the Vet’s orders but get your dog’s blood levels tested if you see any more serious symptoms. begin to improve. Your dog may experience laziness, loss of coordination (ataxia), excessive urination, increased chances of getting thirsty, and excessive eating as it adjusts to the medication. Aminophylline 9. As your dog's body becomes The most common side effects of Pehnobarbital in dogs are: Excessive hunger and thirst: Hunger and thirst levels are usually the number one side effects of phenobarbital in dogs. Phenobarbital induces hepatic enzymes, and it may be difficult to distinguish the effect of enzyme induction on serum liver enzyme activities from actual hepatic damage. Milk thistle is one such natural substance that allows doses Phenobarbital for dogs is inexpensive and as a controlled substance, a doctor or vet’s prescription is needed to obtain it. Long-term administration of phenobarbital has been reported to cause hepatic injury in dogs. Due to its extreme neurological effects, Phenobarbital can yield nasty side effects on large doses. Excessive Urination. It works by making brain cells more resistant to abnormal electrical activity. Other side effects dog owners have seen after giving their dog phenobarbital include: Increased or excessive hunger and/or thirst Dogs taking phenobarbital sometimes experience excessive hunger and thirst and might eat or drink a lot more while on the medication. While it is very popular due to its remarkable effects in controlling canine epilepsy, aside from the fact that it is not approved by the FDA, one of its greatest drawbacks is liver damage. be aware of. 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